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Full Title: | Bayesian Adjustment Methods for Measurement error/Misclassification in Covariates |
Speaker: | Md. Shahadut Hossain, PhD |
Department of Statistics, United Arab Emirates University, UAE | |
Date/Time: | Sunday, January 31, 2010, 12:00PM |
Venue: | ISRT Seminar Room |
In most epidemiological investigations, the study units are people, the outcome variable (or the response) is a health-related event, and the explanatory variables are usually environmental and/or socio-demographic factors. The fundamental task in such investigations is to quantify the association between the explanatory variables (covariates/exposures) and the outcome variable through a suitable regression model. The accuracy of such quantification depends on how precisely the relevant covariates are measured. In many instances, we cannot measure some of the covariates accurately. Rather, we can measure noisy (mismeasured) versions of them. In statistical terminology, mismeasurement in continuous covariates is known as measurement errors or errors-in-variables. Regression analyses based on mismeasured covariates lead to biased inference about the true underlying response-covariate associations. In this talk, I will discuss a flexible parametric approach for avoiding this bias when estimating the response-covariate relationship through a logistic regression model. The performance of the proposed flexible parametric approach has been investigated through extensive simulation studies. Also, the performance of the proposed method has been demonstrated on a real-life data set. Though emphasis is put on the logistic regression model, the proposed method is unified and is applicable to the other generalized linear models, and to other types of non-linear regression models as well.
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Director,
Institute of Statistical Research
and Training (ISRT)
University of Dhaka
Dhaka 1000, Bangladesh